Manuscript Proposals & Publications
Overview of GPPAD manuscript proposals and resulting publications:
2024
- Early-childhood body mass index and its association with the COVID 19 pandemic, containment measures and islet autoimmunity in children with increased risk for type 1 diabetes
S. Hummel, A.G. Ziegler et al. Diabetologia 2024 - Infection episodes and islet autoantibodies in children at increased risk for type 1 diabetes before and during the COVID-19 pandemic
I. Zeller, A.G. Ziegler et al. Infection 2024 - Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes
E. Hendriks, L. Marcovecchio et al. Diabetes Metab Res Rev. 2024 - Vitamin D insufficiency in infants with increased risk of developing type 1 diabetes: a secondary analysis of the POInT Study
A. Jacobs, M. Warnants, V. Vollmuth et al. BMJ Paediatr Open. 2024 - Maternal type 1 diabetes and alterations in blood DNA methylation of their offspring
S. Hummel, R. Ott, A.G. Ziegler
(submitted) - Genetics of circulating proteins in newborn babies identifies drivers of type 1 diabetes risk and therapeutic targets
Proteomics Project done in Dried Blood Spots using samples POInT participants
(in revision)
2023
- SARS-CoV-2 infection is associated with the development of islet autoimmunity in early childhood
E. Bonifacio, M. Lugar, A. Eugster et al. Jama. 2023
2022
- The emotional well-being of parents with children at genetic risk for type 1 diabetes before and during participation in the POInT-study
J. Houben, M. Janssens, C. Winkler et al. Pediatr Diabetes 2022 - Elevations in blood glucose before and after the appearance of islet autoantibodies in children
K. Warncke, A. Weiss, P. Achenbach et al. J Clin Invest. 2022
Manuscript Proposals
- Longitudinal comparison of islet and gut autoantibody detection in infants at high genetic risk for type 1 diabetes by the gold standard radiobinding assays and luciferase immunoprecipitation assays
K. Gillespie (University Bristol, UK), A.G. Ziegler et al
- Investigation of the relationship between HLA/ major autoimmune-variants and microbiome in the pathophysiology of Type 1 Diabetes
Luo, E. Ng, J. Todd et al
- Neutrophil and whole blood counts in children with increased risk for type 1 diabetes
Gemulla, A. Hommel, E. Bonifacio et al
- Early metabolic markers in relation to growth and development of islet autoimmunity in POInT
H. Elding-Larsson et al
- Parental anxiety before and after their child develops islet autoantibodies
Jessica Melin et al
- Analysis plan: Capacity of peripheral blood DNA methylation to predict progression from stage 1 to stage 3 type 1 diabetes in the Fr1da study
C. Relton (University Bristol, UK), A.G. Ziegler et al
- Natural history of autoimmunity in children with increased risk of type 1 diabetes: from birth to insulin-dependency
O. Kordonouri et al
- Tissue transglutaminase and thyroid peroxidase autoimmunity in children with an elevated genetic risk for type 1 diabetes.
M. Sporreiter, E. Bonifacio, A.G. Ziegler
- Single cell multiome signatures to decipher the maternal T1D induced protective mechanisms against islet autoimmunity development (for POInT PBMC samples in Munich and Dresden)
E. Bonifacio, A.G. Ziegler, F. Büttner (University of Frankfurt / DKFZ)
- DNA methylation status in children infected by SARS-CoV-2
E. Bonifacio, R. Ott, T. Singh
- European newborn screening for an increased risk of type 1 diabetes
C. Winkler et al - HbA1c levels in young children with a genetic risk for type 1 diabetes (0-5 years old)
K. Casteels, a. Jacobs et al - Characteristics of children enrolled in GPPAD primary prevention trials POInT and SINT1A
S. Hummel, A. G. Ziegler et al